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SANTOS GARCIA, MARIA MERCEDES

PROFESORES TITULARES DE UNIVERSIDAD
Química Orgánica
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msantos@eii.uva.es
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Índice H en Web of Science: 15
Índice H en Scopus: 18
 
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[][com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=58612]], camposKey:1226-086X 2021-01-25 Production of elastin-like recombinamer-based nanoparticles for docetaxel encapsulation and use as smart drug-delivery systems using a supercritical anti-solvent process361374, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=58613]], camposKey:0141-8130 2020-12-01 Functional characterization of an enzymatically degradable multi-bioactive elastin-like recombinamer16401648, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=58614]], camposKey:1742-7061 2020-10-01 Elastin-like recombinamer-based devices releasing Kv1.3 blockers for the prevention of intimal hyperplasia: An in vitro and in vivo study264274, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=41194]], camposKey:0141-8130 2019-01-01 A novel lipase-catalyzed method for preparing ELR-based bioconjugates752759, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39505]], camposKey:1389-4501 2018-01-01 Elastin-Like Recombinamers as Smart Drug Delivery Systems360379, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=42863]], camposKey:0929-8673 2018-01-01 Genetically Engineered Elastin-based Biomaterials for Biomedical Applications00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=6909]], camposKey:1385-2728 2017-01-01 Advanced Systems for Controlled Drug Delivery from Chemically Modified Elastin-like Recombinamers2133, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=257]], camposKey:2190-4286 2017-01-01 Recombinant DNA technology and click chemistry: a powerful combination for generating a hybrid elastin-like-statherin hydrogel to control calcium phosphate mineralization772783, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=283]], camposKey:1543-8384 2016-01-01 Biocompatible ELR-Based Polyplexes Coated with MUC1 Specific Aptamers and Targeted for Breast Cancer Gene Therapy795808, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=294]], camposKey:0957-4530 2015-01-01 Biocompatible elastin-like click gels: design, synthesis and characterization1050, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=269]], camposKey:1742-7061 2015-01-01 Elastin-like recombinamer-covered stents: Towards a fully biocompatible and non-thrombogenic device for cardiovascular diseases146155, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=271]], camposKey:1549-3296 2015-01-01 Elastin-like recombinamers with acquired functionalities for gene-delivery applications31663178, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=309]], camposKey:1742-7061 2014-01-01 Cellular uptake of multilayered capsules produced with natural and genetically engineered biomimetic macromolecules26532662, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=6915]], camposKey:1932-6254 2014-01-01 Development of a delivery system based on elastin like recombinamers (ELRs) for glaucoma treatment360360, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=270]], camposKey:1742-7061 2014-01-01 Elastin-like recombinamer catalyst-free click gels: Characterization of poroelastic and intrinsic viscoelastic properties24952505, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=6917]], camposKey:1568-0266 2014-01-01 Recent Contributions of Elastin-Like Recombinamers to Biomedicine and Nanotechnology819836, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=260]], camposKey:0032-3861 2014-01-01 The effect of NaCl on the self-assembly of elastin-like block co-recombinamers: Tuning the size of micelles and vesicles53145321, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=274]], camposKey:1525-7797 2013-01-01 Efficient Cell and Cell-Sheet Harvesting Based on Smart Surfaces Coated with a Multifunctional and Self-Organizing Elastin-Like Recombinanner18931903, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=50224]], camposKey:1932-6254 2013-01-01 Internalization of biomimetic microcapsules for intracellular delivery of active agents160, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=50987]], camposKey:0931-7597 2010-01-01 ChemInform Abstract: Synthesis and Photooxygenation of (S)-p-Tolylsulfinylfuran Derivatives.00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=253]], camposKey:1022-1336 2010-01-01 Gold Tailored Photosensitive Elastin-like Polymer: Synthesis of Temperature, pH and UV-vis Sensitive Probes568573, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=7937]], camposKey:0022-3263 2007-01-01 Asymmetric synthesis of beta-hydroxy sulfides controlled by remote sulfoxides10351038, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=7945]], camposKey:0040-4020 2006-01-01 Optically pure trans-2,3-disubstituted N-sulfinyl aziridines. Regio- and stereoselective opening mediated by the sulfinyl group85258532, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=7940]], camposKey:1042-6507 2005-01-01 A new access to the synthesis of optically pure beta-aminosulfides14911492, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=7943]], camposKey:0022-3263 2005-01-01 Synthesis of optically pure 1,2-diaryl- and 1,2-alkylaryl-1,2-amino sulfides39143920, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=7938]], camposKey:0957-4166 2004-03-22 Asymmetric synthesis of (3S,4R,5R)-4,5-dihydroxy-3-methyl-2,3,4,5-tetrahydropyridazine: a formal synthesis of 1-azagulofagomine analogues10591063, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=7415]], camposKey:0308-8146 2003-01-01 Variability of brewer's spent grain within a brewery1721, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=50989]], camposKey:0931-7597 2002-01-01 ChemInform Abstract: Mild Regioselective Halogenation of Activated Pyridines with N¿Bromosuccinimide.00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=1820]], camposKey:1618-2642 2002-01-01 Factors affecting the extraction, hydrolysis and derivatization steps for the quantitation of total residues of amitraz in honey by gas chromatography with electron capture detection300304, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=7417]], camposKey:0733-5210 2002-01-01 Pentoses and hydroxycinnamic acids in brewer's spent grain5158, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=7936]], camposKey:0040-4039 2002-01-01 Synthesis and photooxygenation of 2-thiofuran derivatives: a mild and direct access to O,S-dimethyl and O-methyl-S-phenyl thiomaleates91299132, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=7931]], camposKey:0957-4166 2002-01-01 Use of enantiomerically pure methylsulfinylmethylisoxazolines in the stereoselective synthesis of 1,5,6,7-tetrahydroxy-3-heptanone derivatives34473456, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=9976]], camposKey:0039-7881 2001-01-01 Mild regioselective halogenation of activated pyridines with N-bromosuccinimide21752179, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=9973]], camposKey:1523-7060 2000-10-05 First asymmetric hetero Diels-Alder reaction of 1-sulfinyl dienes with nitroso derivatives. A new entry to the synthesis of optically pure 1,4-imino-1-ribitol derivatives31653168, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=7934]], camposKey:0957-4166 2000-01-01 A highly stereoselective synthesis of D-erythrose derivatives by one-carbon homologation of 2,3-O-isopropylidene-D-glyceraldehyde with (R)-methyl p-tolyl sulfoxide789796, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=50988]], camposKey:0931-7597 2000-01-01 ChemInform Abstract: A Highly Stereoselective Synthesis of D-Erythrose Derivatives by One-Carbon Homologation of 2,3-O-Isopropylidene-D-glyceraldehyde with (R)-Methyl p-Tolyl Sulfoxide.00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=9972]], camposKey:0957-4166 2000-01-01 Stereoselective synthesis of 3-alkylsulfinylmethylisoxazolines and their use as chiral nucleophiles in the chain elongation of 2,3-O-isopropylidene-D-glyceraldehyde47914803, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=7951]], camposKey:0957-4166 2000-01-01 Synthesis and photooxygenation of (S)-p-tolylsulfinylfuran derivatives11831191, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=7935]], camposKey:0957-4166 1999-01-01 Stereoselective preparation of O-alkoxy D-tetrose, D-pentose, 2-deoxy-D-glycero tetrose and 2,3-dideoxy-D-erythro pentose derivatives by an iterative elongation of 2,3-O-isopropylidene-D-glyceraldehyde973990, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=9971]], camposKey:0957-4166 1999-01-01 Stereoselective preparation of O-alkoxy D-tetrose, D-pentose, 2-deoxy-D-glycero tetrose and 2,3-dideoxy-D-erythro pentose derivatives by an iterative elongation of 2,3-O-isopropylidene-D-glyceraldehyde (vol 10, pg 973, 1999)22432243, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=9974]], camposKey:0040-4039 1998-01-01 Short enantioselective approach to substituted triazolopyridazines from [(S)R]-1-(1E,3E)-1-p-tolylsulfinyl-1,3-pentadiene14051408, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=9975]], camposKey:0957-4166 1997-01-01 Diels-Alder reactions of [(S)R]-(1E,3E)-1-p-tolylsulfinyl-1,3-pentadiene with monosubstituted ethylenes20932097, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=50985]], camposKey:0931-7597 1996-01-01 ChemInform Abstract: Photooxygenation of Alditol-1-C-yl Derivatives of Furan with Singlet Oxygen.00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39280]], camposKey:0008-6215 1996-01-01 Photooxygenation of alditol-1-C-yl derivatives of furan with singlet oxygen179188, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40602]], camposKey:1130-2283 1995-01-01 C-glycosylfurans .1. A synthesis399406, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=50990]], camposKey:0931-7597 1995-01-01 ChemInform Abstract: Enantioselective Preparation of Alkyl Alkylsulfanylmethyl Sulfoxides and 4,5-Dihydroisoxazoles from Alkanesulfinates of 1,2:5,6-Di-O- isopropylidene-D-glucose.00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39279]], camposKey:0300-922X 1994-01-01 Enantioselective preparation of alkyl alkylsulfanylmethyl sulfoxides and 4,5-dihydroisoxazoles from alkanesulfinates of 1,2 : 5,6-di-O-isopropylidene-D-glucose21772180][CapitolsLlib{id=com.sigma.fs3.argos.domain.gpc.GpcCapitolsLlibPK[ifcactivitat=CAP, ifccomptador=14421]},camposKey: 444 474 Chemical Modification of Biomaterials from Nature Biomaterials from Nature for Advanced Devices and Therapies 1 2016-01-01 -, CapitolsLlib{id=com.sigma.fs3.argos.domain.gpc.GpcCapitolsLlibPK[ifcactivitat=CAP, ifccomptador=14826]},camposKey: 239 268 Bioactive and Smart Hydrogel Surfaces Biomaterials Surface Science 1 2013-10-14 -, CapitolsLlib{id=com.sigma.fs3.argos.domain.gpc.GpcCapitolsLlibPK[ifcactivitat=CAP, ifccomptador=1535]},camposKey: 227 260 Recombinant Antimicrobial Peptides Antimicrobial Polymers 1 2012-01-01 Wiley, CapitolsLlib{id=com.sigma.fs3.argos.domain.gpc.GpcCapitolsLlibPK[ifcactivitat=CAP, ifccomptador=17835]},camposKey: 11 13 Contributor contact details Advances in Textile Biotechnology 1 2010-01-01 Woodhead Publishing, CapitolsLlib{id=com.sigma.fs3.argos.domain.gpc.GpcCapitolsLlibPK[ifcactivitat=CAP, ifccomptador=14422]},camposKey: 235 265 Developments in recombinant silk and other elastic protein fibers for textile and other applications Advances in Textile Biotechnology 1 2010-01-01 Woodhead 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Artículos de revista (47)

Vallejo R.; Gonzalez-Valdivieso J.; Santos M.; Rodriguez-Rojo S.; Arias F.J. Production of elastin-like recombinamer-based nanoparticles for docetaxel encapsulation and use as smart drug-delivery systems using a supercritical anti-solvent process . Journal of Industrial and Engineering Chemistry 2021; 93(0): 361-374.
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Capítulos de libros (5)

Rodríguez Cabello J.C.; González de Torre, I.; Santos, M.; Testera, A.; Alonso Rodrigo, M. Chemical Modification of Biomaterials from Nature. En: -. Biomaterials from Nature for Advanced Devices and Therapies. -; 2016. p. 444-474.
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Proyectos (24)

SCI-IMMUNOPROTECT: LESIÓN MEDULAR AGUDA: INMUNOMODULACIÓN Y NEUROPROTECCIÓN MEDIANTE RECOMBINÁMEROS TIPO-ELASTINA Y ACTIVACIÓN DE LA VÍA DE SEÑALIZACIÓN WNT CANÓNICA.. ARIAS VALLEJO, FRANCISCO JAVIER (IP); SANTOS GARCIA, MARIA MERCEDES; ESCALERA ANZOLA, SARA. DTS19/00162. AGENCIA ESTATAL DE INVESTIGACIÓN, FONDOS FEDER, UNIVERSIDAD DE VALLADOLID (UVa) 2020-2021
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OTROS

Tesis doctorales (1)

SALINAS FERNANDEZ, SORAYA Development of biomaterials based on elastin like recombinamers for 3d bioprinting applications. Universidad de Valladolid; 2020.
 
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Congresos (3)

AYUDAS UVA A LA INVESTIGACION: TERMIS 2014, GENOVA ( ITALIA ) 09/06/2014 -
(Asistencia). SANTOS GARCIA, MARIA MERCEDES. AYUDAS UVA A LA INVESTIGACION: TERMIS 2014
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Patentes (1)

Soraya Salinas Fernández, Jose Carlos Rodriguez Cabello, Matilde Alonso Rodrigo, Mercedes Santos García. Composición a base de biopolímeros recombinantes y usos de la misma como biotinta. P-201831008. 2019.
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