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MOTIÑO GARCÍA-MIGUEL, OMAR

Cargo
INVESTIGADOR DISTINGUIDO JUNIOR
Departamento
Bioquímica y Biología Molecular y Fisiología
 
Correo electrónico
omar.motino@uva.es

Índice H en Scopus: 18
Experto
  • Hígado, Autofagia, Inflamación, Estrés Oxidativo, Muerte celular, Cáncer, enfermedades hepáticas, síndrome metabólico, diabetes, fibrosis
 

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disease00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=87744]], camposKey:1946-6234 2024-01-01 Acyl-CoA binding protein for the experimental treatment of anorexia00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=87745]], camposKey:2041-4889 2024-01-01 Inhibition of acyl-CoA binding protein (ACBP) by means of a GABAAR¿2-derived peptide00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=88630]], camposKey:1554-8627 2024-01-01 Lysosomal damage due to cholesterol accumulation triggers immunogenic cell death00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=79883]], camposKey:1476-4598 2023-12-01 Protein regulator of cytokinesis 1: a potential oncogenic driver00, 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2023-04-01 Involvement of Bcl-2 Family Proteins in Tetraploidization-Related Senescence00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=79888]], camposKey:1554-8627 2023-01-01 Cardio-, hepato- and pneumoprotective effects of autophagy checkpoint inhibition by targeting DBI/ACBP16041606, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=79887]], camposKey:1474-9718 2023-01-01 High plasma concentrations of acyl-coenzyme A binding protein (ACBP) predispose to cardiovascular disease: Evidence for a phylogenetically conserved proaging function of ACBP00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=73595]], camposKey:0027-8424 2022-10-11 ACBP/DBI protein neutralization confers autophagy-dependent organ protection through inhibition of cell loss, 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PUBLICACIONES

Artículos de revista (35)

Nogueira-Recalde U.; Lambertucci F.; Montegut L.; Motiño O.; Chen H.; Lachkar S.; Anagnostopoulos G.; Stoll G.; Li S.; Carbonier V.; Saavedra Diaz E.; Blanco F.J.; van Tetering G.; de Boer M.; Maiuri M.C.; Carames B.; Martins I.; Kroemer G. Neutralization of acyl CoA binding protein (ACBP) for the experimental treatment of osteoarthritis . CELL DEATH AND DIFFERENTIATION 2025; 32(8): 1484-1498

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Capítulos de libros (6)

Omar Motiño; Sijing Li; Flavia Lambertucci; Gerasimos Anagnostopoulos; Léa Montégut; Uxía Nogueira-Recalde; Hui Chen; Maria Chiara Maiuri; Guido Kroemer; Isabelle Martins. A Mouse Model of Hepatocellular Carcinoma Induced by Streptozotocin and High-Fat Diet. En: Guido Kroemer (Editor), Jonathan Pol (Editor), Isabelle Martins (Editor). Liver Carcinogenesis. Springer; 2024. p. 67-75

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AYUDA A LA INVESTIGACIÓN

Proyectos (8)

ESTUDIO DEL POTENCIAL TERAPÉUTICO DE LA INHIBICIÓN DE ACBP/DBI ENCOLANGIOCARCINOMA. Equipo personal investigador: MOTIÑO GARCÍA-MIGUEL, OMAR (IP); SAEZ SANCHEZ, GEMA; LÓPEZ LLANOS, OSCAR. PRONOVUVA2025-07. Entidades Participantes: UNIVERSIDAD DE VALLADOLID (UVa). Entidades Financiadoras: UNIVERSIDAD DE VALLADOLID (UVa). 22/09/2025-31/12/2026

Universidad de Valladolid
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Convenios/Contratos OTC (1)

Contrato Investigador asociado a Proyecto "CONSORCIO PARA EL ESTUDIO DEL FRACASO RENAL AGUDO: FISIOPATOLOGIA, NUEVAS TERAPIAS, BIOMARCADORES Y MODELOS EXPERIMENTALES" con referencia S2017/BMD­3686, CIFRA2_IIBM_COX. Equipo personal investigador: Paloma Martín Sanz (IP); MOTIÑO GARCÍA-MIGUEL, OMAR. Entidades Participantes: AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC).. Entidades Financiadoras: COMUNIDAD DE MADRID.. 01/06/2018

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Otras ayudas y becas (3)

CONTRATO BEATRIZ GALINDO INVESTIGADOR JUNIOR: DEMOSTRAR LA IMPORTANCIA DE LOS ACTIVADORES DE NRF2 COMO DIANA TERAPÉUTICA PARA TRATAR LA ENFERMEDAD DEL HÍGADO GRASO NO ALCOHÓLICO Y PREVENIR SU PROGRESIÓN A CÁNCER HEPÁTICO. MOTIÑO GARCÍA-MIGUEL, OMAR (Director/a). MOTIÑO GARCÍA-MIGUEL, OMAR (Persona beneficiaria). 01/11/2023 - 31/10/2027. 140.000,00 EUR.

JCYL-2Ministerio de Universidades
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OTROS

Congresos (17)

Proceedings of the American Association for Cancer Research Annual Meeting 2024, San Diego (California) ( ESTADOS UNIDOS DE AMÉRICA ) 05/04/2024 - 10/04/2024
(Póster). Sijing Li; Omar Motiño; Flavia Lambertucci; Maria Chiara Maiuri; Isabelle Martins; Guido Kroemer. ACBP/DBI inhibition suppresses NASH-induced hepatocarcinogenesis
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Patentes (1)

Guido Kroemer; Omar Motiño García-Miguel. NEUTRALIZATION OF ACYL-COA BINDING PROTEIN CONFERS AUTOPHAGY-DEPENDENT ORGAN PROTECTION. WO2023/152637. 2023.
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Estancias de investigación (2)

Estancia en el marco del programa CSIC de cooperación científica para el desarrollo ¿I-COOP" del proyecto titulado Papel de la ciclooxigenasa-2 en el daño por isquemia/repefusión en el hígado. 17/10/2017 - 16/11/2017
     CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET). Rosario ( ARGENTINA )


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Cursos y seminarios impartidos (2)

XX Jornada Científica del IIBM: Papel de la ciclooxigenasa-2 en la enfermedad hepatica grasa no alcohólica. Madrid 23/11/2017 - 23/11/2017
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Colaboración en revistas (2)

Revisor. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2022 - 2022
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Líneas de investigación (1)

01/11/2023 Importancia de los activadores de Nrf2 en enfermedad hígado graso no alcohólica y su progresión al cáncer hepático
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Otras actividades (3)

28/06/2024, ASOCIACIÓN ESPAÑOLA DE INVESTIGACIÓN SOBRE EL CÁNCER (ASEICA). Miembro de la ASEICA.
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