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GARCIA RODRIGUEZ, MARIA DEL CARMEN

PROFESOR CONTRATADO DOCTOR
Inmunometabolismo, Infección, Inflamación y Autoinmunidad
 

Índice H en Scopus: 27
 

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activate HIF-1alpha via STAT1 in normoxia and exhibit sex differences in human aortic valve interstitial cells21682179, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40113]], camposKey:0008-6363 2018-04-01 In vitro studies to understand gender differences in calcific aortic valve disease: crosstalk between JAK-STAT and TLR pathways00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40112]], camposKey:1079-5642 2018-01-01 Calcification Induced by Type I Interferon in Human Aortic Valve Interstitial Cells Is Larger in Males and Blunted by a Janus Kinase Inhibitor21482159, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40114]], camposKey:1664-042X 2018-01-01 Toll-Like Receptors, Inflammation, and Calcific Aortic Valve Disease00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39443]], camposKey:1742-2094 2017-01-01 Aging and amyloid beta oligomers enhance TLR4 expression, LPS-induced Ca2+ responses, and neuron cell death in cultured rat hippocampal neurons00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40115]], camposKey:0163-3864 2016-05-01 The Flavone Luteolin Inhibits Liver X Receptor Activation14231428, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39444]], camposKey:1937-6448 2016-01-01 The Calcium-Sensing Receptor in Health and Disease321369, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40119]], camposKey:1932-6203 2014-10-02 Synergy between Sphingosine 1-Phosphate and Lipopolysaccharide Signaling Promotes an Inflammatory, Angiogenic and Osteogenic Response in Human Aortic Valve Interstitial Cells00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40120]], camposKey:1756-4646 2014-09-01 Chemical characterization and anti-inflammatory activity of luteolin glycosides isolated from lemongrass436443, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40123]], camposKey:0378-8741 2013-06-21 Anti-inflammatory activity of Cymbopogon citratus leaves infusion via proteasome and nuclear factor-kappa B pathway inhibition: Contribution of chlorogenic acid126134, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40124]], camposKey:0022-1767 2012-12-01 Lipopolysaccharide and Sphingosine-1-Phosphate Cooperate To Induce Inflammatory Molecules and Leukocyte Adhesion in Endothelial Cells54025410, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40125]], camposKey:0167-5273 2012-06-28 Viral and bacterial patterns induce TLR-mediated sustained inflammation and calcification in aortic valve interstitial cells1825, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40128]], camposKey:0378-8741 2011-01-27 Cymbopogon citratus as source of new and safe anti-inflammatory drugs: Bio-guided assay using lipopolysaccharide-stimulated macrophages818827, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40129]], camposKey:1078-5884 2009-11-01 Varicose Veins Show Enhanced Chemokine Expression635641, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40130]], camposKey:0161-5890 2009-08-01 Differential roles of PI3-Kinase, MAPKs and NF-kappa B on the manipulation of dendritic cell T(h)1/T(h)2 cytokine/chemokine polarizing profile24812492, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40106]], camposKey:0008-6363 2008-08-01 Selective attenuation of Toll-like receptor 2 signalling may explain the atheroprotective effect of sphingosine 1-phosphate537544, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40111]], camposKey:0953-8178 2006-05-01 Francisella tularensis LPS induces the production of cytokines in human monocytes and signals via Toll-like receptor 4 with much lower potency than E. coli LPS785795, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40116]], camposKey:0022-1767 2004-11-01 A new pharmacological effect of salicylates: Inhibition of NFAT-dependent transcription57215729, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40118]], camposKey:0953-8178 2004-10-01 Interaction of endotoxins with Toll-like receptor 4 correlates with their endotoxic potential and may explain the proinflammatory effect of Brucella spp. LPS14671475, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40122]], camposKey:0270-7306 2004-05-01 A conserved docking motif for CK1 binding controls the nuclear localization of NFAT141844195, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39242]], camposKey:0022-1767 2002-09-15 Activation of monocytic cells through Fc gamma receptors induces the expression of macrophage-inflammatory protein (MIP)-1 alpha, MIP-1 beta, and RANTES33213328, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40136]], camposKey:1097-2765 2000-09-01 Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity539550, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40108]], camposKey:0261-4189 2000-09-01 Gene expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun47834795, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40109]], camposKey:0014-2980 2000-08-01 Requirement for integration of phorbol 12-myristate 13-acetate and calcium pathways is preserved in the transactivation domain of NFAT124322436, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40131]], camposKey:0022-1007 1998-06-15 Nuclear factor of activated T cells (NFAT)-dependent transactivation regulated by the coactivators p300 CREB-binding protein (CBP)20312036, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40110]], camposKey:0021-9258 1995-10-20 THE ROLE OF N-GLYCOSYLATION FOR FUNCTIONAL EXPRESSION OF THE HUMAN PLATELET-ACTIVATING-FACTOR RECEPTOR - GLYCOSYLATION IS REQUIRED FOR EFFICIENT MEMBRANE TRAFFICKING2517825184, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40107]], camposKey:0022-1767 1995-06-01 EXPRESSION AND BIOLOGIC CHARACTERIZATION OF THE MURINE CHEMOKINE KC60486057, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40121]], camposKey:0007-1188 1995-02-01 PLATELET-ACTIVATING-FACTOR - THE EFFECTOR OF PROTEIN-RICH PLASMA EXTRAVASATION AND NITRIC-OXIDE SYNTHASE INDUCTION IN RAT IMMUNE-COMPLEX PERITONITIS895901, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40132]], camposKey:0162-3109 1993-07-01 EFFECT OF IMMUNOLOGICAL STIMULATION ON THE PRODUCTION OF PLATELET-ACTIVATING-FACTOR BY RAT PERITONEAL-CELLS - ITS RELEVANCE TO ANAPHYLACTIC REACTIONS7382, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=1096]], camposKey:0021-9258 1993-01-01 Dissociation of platelet-activating factor production and arachidonate release by the endomembrane Ca2+-ATPase inhibitor thapsigargin. Evidence for the involvement of a Ca2+-dependent route of priming in the production of lipid mediators by human polymorphonuclear leukocytes2475124757, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40117]], camposKey:0022-3042 1992-12-01 MUSCARINIC ACETYLCHOLINE-RECEPTOR ENHANCES PHOSPHATIDYLCHOLINE HYDROLYSIS VIA PHOSPHOLIPASE-D IN BOVINE CHROMAFFIN CELLS IN CULTURE22442250, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40133]], camposKey:0021-9258 1991-11-05 COUPLING BETWEEN INTRACELLULAR CA2+ STORES AND THE CA2+ PERMEABILITY OF THE PLASMA-MEMBRANE - COMPARISON OF THE EFFECTS OF THAPSIGARGIN, 2,5-DI-(TERT-BUTYL)-1,4-HYDROQUINONE, AND CYCLOPIAZONIC ACID IN RAT THYMIC LYMPHOCYTES2085620862, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40127]], camposKey:0264-6021 1991-02-01 METABOLISM OF PLATELET-ACTIVATING-FACTOR IN HUMAN HEMATOPOIETIC-CELL LINES - DIFFERENCES BETWEEN MYELOID AND LYMPHOID-CELLS573578, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40126]], camposKey:0022-3565 1990-10-01 1,4-DIHYDROPYRIDINES, A NEW CLASS OF PLATELET-ACTIVATING FACTOR RECEPTOR ANTAGONISTS - INVITRO PHARMACOLOGICAL STUDIES2833, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40135]], camposKey:0264-6021 1990-01-01 Biosynthesis of platelet-activating factor (PAF) in human polymorphonuclear leucocytes: The role of lyso-PAF disposal and free arachidonic acid9198, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=63395]], camposKey:0022-3565 1990-01-01 1,4-Dihydropyridines, a new class of platelet-activating factor receptor antagonists: In vitro pharmacologic studies2833, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=40134]], camposKey:0264-6021 1988-09-15 BIOSYNTHESIS OF PLATELET-ACTIVATING FACTOR IN GLANDULAR GASTRIC-MUCOSA - 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Artículos de revista (40)

Parra-Izquierdo I.; Sanchez-Bayuela T.; Lopez J.; Gomez C.; Perez-Riesgo E.; Roman J.A.S.; Crespo M.S.; Yacoub M.; Chester A.H.; Garcia-Rodriguez C. Interferons are pro-inflammatory cytokines in sheared-stressed human aortic valve endothelial cells . International Journal of Molecular Sciences 2021; 22(19)

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Capítulos de libros (1)

Solá, L.D.R.; González-Fajardo, J.A.; Crespo, M.S.; García-Rodríguez, C. The role of inflammation in the varicose vein pathology: New insights. En: Nelson, A.L. Varicose Veins: Symptoms, Causes and Treatments. Nova Science Publishers; 2011. p. 59-91


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AYUDA A LA INVESTIGACIÓN

Proyectos (8)

PAPEL DEL INMUNOMETABOLISMO EN LA DEFENSA FRENTE A LA INFECCION Y EN EL DESARROLLO DE LA AUTOINMUNIDAD. Equipo Investigadores: FERNANDEZ GARCIA, MARIA NIEVES (IP); SANCHEZ CRESPO BOLAÑOS, JOSE RAMON; GARCIA RODRIGUEZ, MARIA DEL CARMEN; CASTRILLO VIGUERA, ANTONIO JESUS; ALONSO GARCIA, ANDRES; MONTERO DOMINGUEZ, OLIMPIO; BAYON PRIETO, YOLANDA. Personal Contratado: ALVAREZ MUÑOZ, YOLANDA. VA175P20. Entidades colaboradoras LABORATORIOS CALIER S.A.. Entidades Participantes: UNIVERSIDAD DE VALLADOLID (UVa). Entidades Financiadoras: FONDOS FEDER, JUNTA DE CASTILLA Y LEÓN -CONSEJERÍA DE EDUCACIÓN. 28/06/2021-27/06/2024

FEDERJCYL-2
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Convenios/Contratos OTC (7)

EVALUACIÓN DE NUEVOS COMPUESTOS ANTIINFLAMATORIOS AISLADOS DE PLANTAS. . Equipo Investigadores: GARCIA RODRIGUEZ, MARIA DEL CARMEN (IP). Entidades Participantes: FUNDACION GENERAL DE LA UNIVERSIDAD DE VALLADOLID.. Entidades Financiadoras: FUNDACION UNIVERSIDAD DE VALLADOLID M.P.., UNIVERSIDAD DE VALLADOLID.. 01/11/2013

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Otras ayudas y becas (4)

CONTRATO PREDOCTORA UVA DE MIRIAM PERAL RODRIGO: INMUNIDAD, METABOLISMO Y ESTRÉS DE RETÍCULO EN LA PATOGENIA DE LA ESTENOSIS AÓRTICA CALCIFICADA. GARCIA RODRIGUEZ, MARIA DEL CARMEN (Director). PERAL RODRIGO, MIRIAN (Beneficiario). 01/05/2022 - 30/04/2026. 92.435,50 EUR.

Banco SantanderUniversidad de Valladolid
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OTROS

Tesis doctorales (6)


 
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Patentes (1)

Mª Carmen García Rodríguez. Uso de inhibidores de receptores de S1P para el tratamiento de la estenosis aórtica calcificada. P-201130365/PCT/ES2012/070170. 2011.
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