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FERNANDEZ GARCIA, MARIA NIEVES

PROFESORES TITULARES DE UNIVERSIDAD
Bioquímica y Biología Molecular y Fisiología
Inmunometabolismo, Infección, Inflamación y Autoinmunidad
 
nieves.fernandez@uva.es

Índice H en Scopus: 17
 

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com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39234]], camposKey:0026-895X 2014-01-01 Polarization of the Innate Immune Response by Prostaglandin E-2: A Puzzle of Receptors and Signals187197, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39233]], camposKey:0021-9258 2014-01-01 The Unfolded Protein Response and the Phosphorylations of Activating Transcription Factor 2 in the trans-Activation of il23a Promoter Produced by beta-Glucans2294222957, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39235]], camposKey:1932-6203 2013-01-01 The Response of Human Macrophages to beta-Glucans Depends on the Inflammatory Milieu00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39236]], camposKey:0021-9258 2012-01-01 Sirtuin 1 Is a Key Regulator of the Interleukin-12 p70/Interleukin-23 Balance in Human Dendritic Cells3568935701, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39238]], camposKey:0161-5890 2011-01-01 Apoptotic cells enhance IL-10 and reduce IL-23 production in human dendritic cells treated with zymosan97106, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39239]], camposKey:0021-9258 2011-01-01 Notch- and Transducin-like Enhancer of Split (TLE)-dependent Histone Deacetylation Explain Interleukin 12 (IL-12) p70 Inhibition by Zymosan1658316595, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39240]], camposKey:0962-9351 2010-01-01 Eicosanoids in the Innate Immune Response: TLR and Non-TLR Routes00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39244]], camposKey:0022-3565 2009-01-01 Cyclooxygenase-2 Induced by Zymosan in Human Monocyte-Derived Dendritic Cells Shows High Stability, and Its Expression Is Enhanced by Atorvastatin987994, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39243]], camposKey:0022-1767 2009-01-01 The Induction of IL-10 by Zymosan in Dendritic Cells Depends on CREB Activation by the Coactivators CREB-Binding Protein and TORC2 and Autocrine PGE(2)14711479, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39226]], camposKey:0022-1767 2008-01-01 Costimulation of dectin-1 and DC-SIGN triggers the arachidonic acid cascade in human monocyte-derived dendritic cells57275736, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39227]], camposKey:0014-2980 2007-01-01 Mannan and peptidoglycan induce COX-2 protein in human PMN via the mammalian target of rapamycin25722582, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39228]], camposKey:0741-5400 2007-01-01 Peptidoglycan and mannose-based molecular patterns trigger the arachidonic acid cascade in human polymorphonuclear leukocytes925933, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=6860]], camposKey:0741-5400 2006-01-01 Coupling of C3bi to IgG inhibits the tyrosine phosphorylation signaling cascade downstream Syk and reduces cytokine induction in monocytes10731082, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=10091]], camposKey:0030-3747 2006-01-01 Intraretinal immunohistochemistry findings in proliferative vitreoretinopathy with retinal shortening193200, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=42096]], camposKey:0960-8931 2005-01-01 Efficacy of five human melanocytic cell lines in experimental rabbit choroidal melanoma2937, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39230]], camposKey:0022-1767 2005-01-01 Mannose-containing molecular patterns are strong inducers of cyclooxygenase-2 expression and prostaglandin E-2 production in human macrophages81548162, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=16749]], camposKey:0165-6147 2004-01-01 Blood and endothelium in immune complex-mediated tissue injury512517, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=10380]], camposKey:0030-3747 2003-01-01 Proliferative vitreoretinopathy: Cytologic findings in vitreous samples232238, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39237]], camposKey:0021-9258 2003-01-01 Release of arachidonic acid by stimulation of opsonic receptors in human monocytes - The Fc gamma R and the complement receptor 3 pathways5217952187, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39242]], camposKey:0022-1767 2002-09-15 Activation of monocytic cells through Fc gamma receptors induces the expression of macrophage-inflammatory protein (MIP)-1 alpha, MIP-1 beta, and RANTES33213328, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39241]], camposKey:0014-2980 2002-01-01 Fc gamma R receptors activate MAP kinase and up-regulate the cyclooxygenase pathway without increasing arachidonic acid release in monocytic cells383392, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=10394]], camposKey:0960-8931 2002-01-01 The need for continuous immunosuppression with cyclosporin A to maintain an experimental model of uveal melanoma441447, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=49644]], camposKey:0365-6691 2001-01-01 Comparison of different techniques for cytologic analysis of vitreous specimens Comparación de diferentes técnicas de análisis citológico en muestras vítreas.723730, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=49641]], camposKey:0365-6691 2001-01-01 Efficacy of direct paraffin embedding in cytological analysis of vitreous from proliferative vitreo-retinopathy (PVR) Eficacia de la inclusión directa en parafina en el estudio citológico del vítreo en pacientes con vitreorretinopatía proliferante (VRP).655660, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39245]], camposKey:0014-2980 2001-01-01 Fc gamma RIIA exogenously expressed in HeLa cells activates the mitogen-activated protein kinase cascade by a mechanism dependent on the endogenous expression of the protein tyrosine kinase Syk13611369, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39247]], camposKey:0013-7227 2000-01-01 Atypical protein kinase C-zeta stimulates thyrotropin-independent proliferation in rat thyroid cells146152, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=741]], camposKey:1080-7683 1998-01-01 Expression of ICAM-1 and HLA-DR by human conjunctival epithelial cultured cells and modulation by nedocromil sodium517531, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=39246]], camposKey:0021-9258 1997-01-01 Beta 2-chimaerin is a high affinity receptor for the phorbol ester tumor promoters2648826496, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=10431]], camposKey:0271-3683 1997-01-01 Morphologic and immunocytochemical characterization of four human uveal cell lines (melanoma- and melanocytes-derived)487495, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=41438]], camposKey:0146-0404 1996-01-01 Growth of a human uveal melanoma cell line in rabbits immunosuppressed with different doses of cyclosporin A (CsA)00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=41437]], camposKey:0146-0404 1996-01-01 Nedocromil Sodium (NS) modulates ICAM-1 and HLA-DR expression of human conjunctival epithelial cells in vitro00, com.sigma.fs3.argos.domain.gpc.GpcArticlesRev[id=com.sigma.fs3.argos.domain.gpc.GpcArticlesRevPK[ifcactivitat=ARE, ifccomptador=41439]], camposKey:0365-6691 1995-01-01 Immunocytochemical and morphological characterization of three uveal melanoma cell lines CARACTERIZACION MORFOLOGICA E INMUNOCITOQUIMICA DE TRES LINEAS CELULARES DE MELANOMA UVEAL HUMANO609616, 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Artículos de revista (41)

Mancebo C.; Fernandez J.J.; Herrero-Sanchez C.; Alvarez Y.; Alonso S.; Sandoval T.A.; Cubillos-Ruiz J.R.; Montero O.; Fernandez N.; Crespo M.S. Fungal Patterns Induce Cytokine Expression through Fluxes of Metabolic Intermediates That Support Glycolysis and Oxidative Phosphorylation . JOURNAL OF IMMUNOLOGY 2022; 208(12): 2779-2794.

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Proyectos (2)

PAPEL DEL INMUNOMETABOLISMO EN LA DEFENSA FRENTE A LA INFECCION Y EN EL DESARROLLO DE LA AUTOINMUNIDAD. Equipo Investigadores: FERNANDEZ GARCIA, MARIA NIEVES (IP); SANCHEZ CRESPO BOLAÑOS, JOSE RAMON; GARCIA RODRIGUEZ, MARIA DEL CARMEN; CASTRILLO VIGUERA, ANTONIO JESUS; ALONSO GARCIA, ANDRES; MONTERO DOMINGUEZ, OLIMPIO; BAYON PRIETO, YOLANDA. Personal Contratado: ALVAREZ MUÑOZ, YOLANDA. VA175P20. Entidades colaboradoras LABORATORIOS CALIER S.A.. Entidades Participantes: UNIVERSIDAD DE VALLADOLID (UVa). Entidades Financiadoras: FONDOS FEDER, JUNTA DE CASTILLA Y LEÓN -CONSEJERÍA DE EDUCACIÓN. 28/06/2021-27/06/2024

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CONTRATO POSDOCTORAL RAMÓN Y CAJAL DE MARÍA NIEVES FERNÁNDEZ GARCÍA: ANALISIS MOLECULAR DE LA REACCION INFLAMATORIA DESENCADENADA POR LA ESTIMULACION DE LOS FC GAMMA R, LO QUE PERMITIRA COMPRENDER MEJOR LOS MECANISMOS PATOGENICOS EN LAS ENFERMEDADES PRODUCIDAS POR DEPOSITO DE MATERIAL INMUNE EN LOS TEJIDOS Y ELABORAR ESTRATEGIAS TERAPEUTICAS.. FERNANDEZ GARCIA, MARIA NIEVES (Director). FERNANDEZ GARCIA, MARIA NIEVES (Beneficiario). 01/07/2004 - 30/06/2009. 203.945,00 EUR.

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